Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human ...

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

The neocortex is the largest and most complex part of the brain and has long been considered the ultimate storage site for long-term memories. But how are traces of past events and experiences laid ...

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20 th in the ...

The neocortex stands out as a stunning achievement of biological evolution. All mammals have this swath of tissue covering their brain, and the six layers of densely packed neurons within it handle ...

The neocortex is the largest and most complex part of the brain and has long been considered the ultimate storage site for long-term memories. But how are traces of past events and experiences laid ...

UCLA scientists have produced one of the first high-resolution molecular maps showing how Down syndrome disrupts human brain development before birth. The study analyzed over 100,000 nuclei from ...

Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice. Those are the findings of a new study conducted by Charité – Universitätsmedizin Berlin and ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment and the brain later in life, investigators at Johns Hopkins Medicine and ...