A new report presents DM-Seq (direct methylation sequencing), a bisulfite-free method for profiling 5-methylcytosine (5mC) at single-base resolution using nanogram quantities of DNA. The technique ...
Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...
In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...
A new DNA sequencing technique that delivers faster and more accurate bacterial infection diagnoses could be implemented nationwide. The method, developed by the Medicines and Healthcare products ...
Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...
Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...
Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...
Advances in DNA sequencing technology help forensic biologists identify suspects where traditional DNA profiling has failed, ...