Here we present HiC-DC, a principled method to estimate the statistical significance (P values) of chromatin interactions from Hi-C experiments. HiC-DC uses hurdle negative binomial regression account ...
In this paper we consider nonlinear models with an arbitrary number of covariates for which the information additionally depends on the value of the linear predictor. We establish the general result ...
The candidate malaria vaccine RTS,S/AS01E has entered phase 3 trials, but data on long-term outcomes are limited. Over a period of 4 years, 118 of 223 children who received the RTS,S/AS01E vaccine and ...
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