Functional safety engineers follow the ISA/IEC 61511 standard and perform calculations based on random hardware failures. These result in very low failure probabilities, which are then combined with ...

In genetic analysis, there are often competing explanations for the same data. Sophisticated mathematical models have been developed that can encapsulate these problems in terms of parameters that ...

Introduction: Bayesian data mining methods have been used to evaluate drug safety signals from adverse event reporting systems and allow for evaluation of multiple endpoints that are not prespecified.

We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...

With the prevalence of gene expression studies and the relatively low reproducibility caused by insufficient sample sizes, it is natural to consider joint analysis that could combine data from ...