High-resolution 3D image showing how the 5-HT1A receptor connects with internal signaling proteins (G proteins). The highlighted areas reveal key contact points between the receptor and two different ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid receptors. What they didn't know—until now—was exactly what happens next.

Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and ...

The AMPA group of brain receptors have mostly been assumed to be calcium impermeable and so were not thought to contribute to the calcium-dependent mechanisms underlying learning and memory.