Researchers have redesigned lipid nanoparticles to make mRNA vaccine delivery more precise, reducing off-target effects.

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to ...

A new nanoparticle design directs mRNA vaccines to lymph nodes. The strategy reduced off-target delivery, maintained immune ...

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise ...

A more effective vaccine technology may be on the horizon. In a new study in mice, researchers from the University of Copenhagen demonstrate that a simple addition to mRNA vaccines can significantly ...

The United States may be losing its edge in mRNA technology­­. The technology, which powered life-saving COVID-19 vaccines and is now rocketing new cancer therapeutics forward, will soon undergo a ...

N4-Acetylation of cytidine (ac4C) is an mRNA modification that enhances cellular mRNA stability and translation. Most eukaryotic organisms catalyze ac4C using a homologue of human N-acetyltransferase ...