Both hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are characterized by thrombotic microangiopathy (TMA), affecting mainly the kidney and brain, respectively. Diagnosis ...

Investigators found patients with acute coronary syndrome were 3 times more likely to die in the hospital. Patients with thrombotic thrombocytopenic purpura (TTP) face a higher risk of morbidity and ...

For all primary TMA syndromes, the vascular pathological abnormalities that are observed in routine specimens are the same, as illustrated in the center of the figure by the renal arteriole occlusion ...

Acquired thrombotic thrombocytopenic purpura (acquired TTP, or aTTP) is a rare blood disorder that results in blood clots in small blood vessels around your body. These clots can slow the flow of ...

Molecular details of ADAMTS13 binding by autoantibodies reveal, for the first time, the mechanism of inhibition of ADAMTS13 by those autoantibodies and suggest an avenue for therapeutic intervention.

A key opinion leader explains how acquired TTP is diagnosed, with a focus on the use of ADAMTS13 testing. X. Long Zheng, MD, PhD: How do you actually diagnose TTP [thrombotic thrombocytopenic purpura] ...

An organism provisionally classified as a microtatobiote, order of rickettsiales, family of bartonellaceae, was isolated from two patients with hemolytic-uremic syndrome (HUS) and from another with ...