Human sperm have long been a subject of fascination—not just for their role in fertilization, but for their remarkable ability to navigate through some of the most viscous environments in the body.

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

Research into how a father’s choices — such as diet, exercise, stress, nicotine use — may transfer traits to his children has ...

Jaiwen Hsu was an active 11-year-old when he developed pain in his left knee that forced him to sit out a few soccer games. What his parents thought was a sports injury turned out to be osteosarcoma, ...

A man in his early 20s received a transplant of his own sperm-producing stem cells, which had been frozen since his childhood, in an attempt to regain fertility. Doctors are waiting to see if the ...

The evolutionary origin of sperm can be traced back to a single-celled ancestor of all living animals. Almost all animals reproduce by having a single-celled stage of their life cycle, involving two ...

When sperm meets egg, the start of life is not quiet. Under a special microscope, researchers have watched a tiny light show at fertilization. They see a microscopic flash at fertilization, a burst of ...

Researchers at the Columbia University Fertility Center reported the first successful pregnancy using an AI-guided method they developed to recover sperm in men with azoospermia, in which ejaculate ...

Male fertility rates have been plummeting over the past half-century. An analysis from 1992 noted a steady decrease in sperm counts and quality since the 1940s. A more recent study found that male ...