The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex ...

The pyruvate dehydrogenase complex consists of many different enzymes (marked in different colours). Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to ...

Having considered localization of respiratory functions in mitochondria and in prokaryotic cells, it's time to return to the ...

Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a mitochondrial proline-metabolizing enzyme, as a third structural component of the ...