Lysine methylation is a pivotal post‐translational modification that modulates protein function by the addition of methyl groups to the ε‐amine of lysine residues. This modification, catalysed by ...
Nutritional status and quality of life in patients with gastric cancer in China. The methylation of hMLH1 was related to alcohol, CA199 level and Borrman. The methylation of CDH1 was related to the ...
In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...
Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via ...
The amino acid side chains of proteins undergo various post-translational modifications (PTMs) which significantly impact protein function and mediate complex cellular events. Measuring the dynamics, ...
Successful pregnancy requires coordinated physiological processes, with m⁶A participating in critical stages: i) Folliculogenesis: m⁶A dynamically regulates oocyte-granulosa cell crosstalk during ...
AI protein function prediction is reshaping how laboratories approach protein annotation, hypothesis generation, and translational research. As sequencing technologies continue to outpace experimental ...
A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics. Many ...
Editor’s note: Nathan Ahlgren is an assistant professor of biology at Clark University. In this interview, he explains exactly what proteins are, how they are made, and the wide variety of functions ...