A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Microscopes have long been scientists’ eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

The microscope combines a big telecentric photolithography lens with a large tube lens to create sharp, detailed images of large and curved samples. These lenses project the image onto a flat array of ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...

In-vivo imaging of the neuronal activity in mouse primary visual cortex. Left, high-resolution neuronal map; middle, high-speed neuronal activity recording captured by the two-photon microscope with ...