Please provide your email address to receive an email when new articles are posted on . Patients given aerosolized 4D-710 had elevated CFTR protein levels that went over normal levels. Over 12 months, ...

Adding either of two new drugs — VX-659 or VX-445 — to the standard tezacaftor-ivacaftor combination improves both lung function and sweat chloride concentrations in most patients with cystic fibrosis ...

CFTR is a protein essential to wet surfaces throughout your body, like the airways of your lungs. People with cystic fibrosis have a gene mutation that causes problems with the protein. Some ...

The first CF rat model, CFTR tm1sage (termed CFTR-/- or KO), was designed in collaboration with SAGE (now Horizon Discovery) and subsequently characterized at UAB and distributed to the CF community.

An experimental drug suggests that a 'path is clearly achievable' to treat currently untreatable cases of cystic fibrosis disease caused by nonsense mutations. This includes about 11 percent of cystic ...

Established in 2002, the Animal and Preclinical Models Core serves to provide specialized capabilities for developing and characterizing numerous CF animal models relevant to CF pathogenesis and ...

North Chicago, Illinois — A research team at Rosalind Franklin University of Medicine and Science has developed a promising new therapeutic approach for the treatment of cystic fibrosis, a devastating ...

Since emerging in December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 353 million people and caused over 5.6 million deaths worldwide. Severe and fatal ...