Researchers created a new kind of cancer drug that can grab a mutant protein while also carrying a second hit against the ...

Researchers at the University of Michigan have identified a novel way to counter drug resistance in KRAS-mutant non-small ...

A new study has, for the first time, settled the debate about how a mutated protein present in half of all human cancers drives tumor growth. The discovery will not only facilitate a rethink of the ...

Researchers have solved a mystery about the most important driver of cancer development - a mutant protein found in half of all cancers - and how it contributes to tumor growth. Researchers from WEHI ...

In many neurodegenerative disorders, abnormal proteins progressively aggregate and propagate in the brain. But what comes first, aggregation or propagation? Researchers from Japan share some new ...

Adagrasib, an oral small-molecule inhibitor of mutant KRAS G12C protein, has shown clinical activity in pretreated patients with several tumor types, including colorectal cancer. Preclinical studies ...

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging ...

In patients with Huntington’s disease, proteins misfold and clump together. Researchers imagine the treatment could potentially someday be administered as a once-weekly injection to delay disease ...

Respiratory infections, pink eye, or an upset stomach may seem like unrelated, mild inconveniences, but all of these ailments share one root cause: adenovirus infection. Many of us will encounter some ...

Researchers from Tokyo Medical and Dental University (TMDU) show that the protein involved in Parkinson’s disease, α-synuclein, can propagate through the lymphatic system of the brain before it ...