The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Mutations in a calcium ion channel anoctamin 5 (ANO5), commonly found in muscle cells, cause the debilitating disease called limb girdle muscular dystrophy 2L (LGMD2L). Characterized by progressive ...

For decades, statins have been the quiet workhorses of cardiology, cutting heart attack and stroke risk for millions while ...

Taking Vitamin C and calcium together improves gut calcium absorption and may also enhance bone and immune system health.

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Calcium is critical for bone health, optimal muscle activity, and other body processes such as blood clotting and heart function. How much calcium you need depends on your age and stage of life. Share ...

Making sure that your workout is working for you can be one of the most important parts of planning out your fitness journey, but what is muscle activation and how can you go about achieving it?

Calcium is an essential nutrient needed by all living creatures, including humans. Vitamin D is a prohormone that helps the body absorb calcium, which is essential for bone health. Bones and teeth ...

“Your bones are constantly remodeling, which means they are repeatedly breaking down old bone and rebuilding new,” says Callins. Adequate calcium helps support this process, giving bones the resources ...

Calcium is an essential nutrient for strong, healthy bones and teeth. Although a person may be able to get the calcium they need from their diet, some people need extra support from a calcium ...