Gut

CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...
Frontiers

Macrophages: Allies or merciless enemies in musculoskeletal systems

Tissue-resident macrophages are present in virtually every organ of the body to execute a variety of vital functions and ensure tissue integrity and functionality. Single-cell RNA sequencing ...
Kaleido Scope

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal function

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...
EurekAlert!

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal function

The understanding of how macrophages regulate their response to toxic particles via two independent pathways could uncover therapeutic opportunities to quell inflammation BIRMINGHAM, Ala. – Human ...