Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable ...

Tissue-resident macrophages are present in virtually every organ of the body to execute a variety of vital functions and ensure tissue integrity and functionality. Single-cell RNA sequencing ...

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor.

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

Even its name is a testament to how enigmatic the tingible macrophage has been. Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known ...

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, ...

Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...

Tumors contain macrophages, immune cells capable of fighting cancer, but their function is suppressed by the tumor, ...

Metastatic disease—when cancer spreads from the primary tumor to other parts of the body—is the cause of most cancer deaths. While researchers understand how cancer cells escape the primary site to ...