Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — ...

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes. Despite advances in surgery and chemotherapy, ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

A protein called LENG8 traps defective RNA molecules inside the cell nucleus before they can reach the cytoplasm and disrupt normal cellular function, according to a study published in Molecular Cell ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...

Impact of variant allele frequency (VAF) of TP53 alterations and Signatera circulating tumor DNA (ctDNA) monitoring for patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab ...