The innate immune response constitutes the body’s first line of defence against pathogens, utilising a network of pattern recognition receptors (PRRs) and signalling molecules to detect and neutralise ...
In a recent review published in Nature Reviews Immunology, researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field. Galectins comprise ...
Scientists at UCSF QBI, University College London and the Icahn School of Medicine at Mount Sinai reported breakthrough findings in a study published Sept. 21, 2023, on convergent evolutionary ...
Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...
A section of Goodsell et al.’s magnificent “Integrative illustration for coronavirus outreach” highlighting the packaging of the viral genetic material (in pink) by the scaffold “nucleocapsid protein” ...
Our immune system is divided into two main branches: innate and adaptive. Innate immune cells act as a first line of defense, quickly responding to invaders, while adaptive immune cells take a longer ...
A recent review published in PLOS Pathogens discussed the current research on the role of molecular mechanisms in mediating immune priming in insects and regulating vector-borne disease transmission.
Historically, inflammation against self was considered autoimmune, a concept that stems back to the seminal observations by Ehrlich, who described serum factors now known to be autoantibodies produced ...
Our immune system works to fight infections immediately, but also maintain long-term immunity. Two waves of protection help neutralize and eliminate disease, including the innate and adaptive immune ...
Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer ...