Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

With no major advances in understanding its underlying mechanisms, inhalational anesthesia is kind of a Victorian-era solution in a healthcare industry fueled by innovation. A medical and ...

Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opioids and ...

The choice of anaesthetic technique in cardiac surgery extends beyond mere sedation, playing a pivotal role in myocardial protection. Both total intravenous anaesthesia (TIVA) and inhalational ...

Cannabis users aged 65 years or older undergoing general anesthesia for surgery required higher doses of inhalational anesthetics than nonusers. However, the clinical relevance of this difference ...

Continuous exposure to high levels of waste anesthetic gas (WAG) poses risks to human health. Institutional animal care and use programs are therefore encouraged to require scavenging of WAG during ...

New research has highlighted the value of recycling general anaesthetic used in routine operations.In the UK, healthcare accounts for more than five per cent of national greenhouse gas emissions, and ...

Acute neuronal injury has devastating consequences with increased risks of morbidity and mortality. Among its survivors, neurological deficit is associated with loss of function, independence and ...