Oocytes are among the longest-lived cells. Scientists have been trying to understand what enables such longevity, because oocytes—like other nondividing, long-lasting cells—have a high risk of ...

The exchange of the oocyte’s genome with the genome of a somatic cell, followed by the derivation of pluripotent stem cells, could enable the generation of specific cells affected in degenerative ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

ELVAs pictured under a microscope. The ‘superorganelle’ roams the cytoplasm, capturing and holding onto toxic protein aggregates to protect oocytes from their toxic effects. Oocytes are immature egg ...