New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in the parents’ lysosomes that promote longevity are transferred to their offspring.

Epigenetics, the dynamic regulation of genetic expression, involves complex molecular mechanisms. While the process of gene silencing by methylating the H3K27 position in histones is understood, not ...

Most of us know that our genes determine our traits—but that's only half the story. The field of epigenetics has reshaped how scientists think about gene regulation, revealing layers of control beyond ...

Epigenetic clocks provide a molecular framework for assessing biological ovarian age by integrating DNA methylation patterns with hallmarks of reproductive aging. While these clocks show moderate ...

A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations—with inherited health problems worsening many generations after exposure. Those ...

By Dr. Liji Thomas, MD A longitudinal study shows that puberty may reprogram children’s epigenetic profiles in ways that ...

A single exposure to a toxic fungicide during pregnancy can increase epigenetic disease risk for 20 subsequent generations.

Studies find genetic, epigenetic, and transgenerational effects from pesticide exposure, particularly during early life.