This guidance emphasises the potential of NGS methods in mitigating safety risks associated with therapies incorporating ...

The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing ...

In a recent study published in the Microorganisms journal, researchers in China reviewed the uses of bacterial-artificial-chromosome (BAC)-based genome editing techniques in herpesvirus research.

CRISPR is a gene editing technique with incredible potential. But the traditional CRISPR-Cas9 approach involves cutting the double helix of DNA in cells, which can have many unintended and dangerous ...

PHILADELPHIA— A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach ...

A novel genome editing technique, NICER, is based on the creation of multiple nicks in single DNA strands by nickase. The method can correct heterozygous mutations using two mechanisms: multiple nicks ...

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes. However, this process is associated with side effects including unwanted mutations ...

Add Yahoo as a preferred source to see more of our stories on Google. Gene editing fixed brain mutations in mice with AHC, offering hope for treating rare neurological diseases at the DNA level.

A powerful new approach for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes—which are commonly used to build drug molecules—has been developed. The ...