Scientists and physicians can better assess precision genome editing technology using a new method made public today by St.

Hutchinson-Gilford Progeria Syndrome is a childhood disorder caused by mutations in one of the major architectural proteins of the cell nucleus. In HGPS patients the cell nucleus has dramatically ...

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes. However, this process is associated with side effects including unwanted mutations ...

A novel genome editing technique, NICER, is based on the creation of multiple nicks in single DNA strands by nickase. The method can correct heterozygous mutations using two mechanisms: multiple nicks ...

For the first time, scientists have found a way to efficiently and precisely remove genes from white blood cells of the immune system and to substitute beneficial replacements, all in far less time ...

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing ...

Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature ...

PHILADELPHIA— A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach ...

Researchers have developed a new "color-coded" genetic method that makes it easy to distinguish male and female mosquitoes. This innovation can help solve a major bottleneck in mosquito control ...