A study explains how broken DNA during cell division can trigger chromoanasynthesis when two repair pathways combine, causing erratic copying and large DNA duplications, offering potential targets for ...

Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is ...

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Cardiff University researchers discovered how a particularly severe type of DNA damage occurs, giving fresh insight into mutation mechanisms that contribute to cancer and inherited genetic diseases.

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression. Research has identified a critical DNA repair ...

Scientists have identified a mechanism that cells use to repair damage in DNA that is associated with aging and health conditions like cancer and ALS (also known as motor neuron disease). In this ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...