The most frequent symptom of mild to moderate PAD is claudication, which is estimated to occur in about a third of patients with PAD in the US. 8 Claudication is defined as cramping, aching, tiredness ...

“Claudication is a condition that involves pain, cramping, or weakness in the muscles, usually in the legs, during physical activity. This discomfort is typically caused by insufficient blood flow to ...

For the IRONIC trial, investigators led by Joakim Nordanstig, MD, PhD, of Sahlgrenska University Hospital (Gothenburg, Sweden), randomized 158 patients with stable intermittent claudication to ...

The pathophysiology of intermittent claudication (IC) and the role of pentoxifylline and cilostazol for treating IC are discussed. IC, a result of inadequate blood flow to the musculature, is the ...

Exercise therapy -- preferably a supervised walking program -- should always be considered as part of the initial therapy for patients with intermittent claudication. [1] Regular walking can be ...

It strikes when you walk — a distinct pain or cramping in your calf. You stop for a few minutes, and the pain goes away. You continue on, and the pain comes back. This leg pain may be claudication. It ...

The National Institute for Health and Care Excellence (NICE) has today issued final guidance recommending naftidrofuryl oxalate as an option for the treatment of people who have intermittent ...

1 Department of Physiotherapy, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia 2 Musculoskeletal Division, Centre for Evidence-Based Physiotherapy, The George Institute for Global ...

Claudication, which means “to limp”, is defined as a pain or discomfort in the lower limb muscles [legs, thighs, or buttocks] that is made worse by walking and relieved with rest. Although a number of ...

Peripheral arterial disease, also known as peripheral vascular disease, is a condition in which arteries that carry blood to the legs (or less commonly the arms) are narrowed or blocked. The usual ...