Researchers from Osaka University find that neuronal activity induces gene expression at the preprepared histone acetylation sites in the nucleus by influencing transcription factors and chromatin ...
The TAZ1 domain of CREB binding protein is crucial for transcriptional regulation and recognizes multiple targets. The interactions between TAZ1 and its specific targets are related to the cellular ...
Kolm Therapeutics Inc. has disclosed heterobifunctional compounds comprising a disease-dependent protein binding moiety (particularly, CREB-binding protein [CREBBP; CBP] or histone acetyltransferase ...
Before I review any site in this column, I search my database of previous reviews. I was surprised to discover that not only had I not previously reviewed this site, but also that I had only covered ...
3+2 Pharma LLC has divulged pyrazole-containing CREB-binding protein (CREBBP; CBP)/β-catenin (CTNNB1) interaction inhibitors reported to be useful for the treatment of fibrosis, cancer, aging, ...
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