Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...

These immune CD8 T cells may provide a target for treating the buildup of fatty lesions in the arteries called atherosclerosis. Atherosclerosis is the underlying pathology of heart attacks and strokes ...

Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...

Colorectal cancer breaks the usual immune rules, with certain regulatory T cells linked to improved survival. In many solid ...

Fapon Biopharma, a biotech in developing therapeutic biologics including cytokine-antibody fusion proteins and T-cell engagers, announced the publication of pioneering research on FP008, a novel ...

New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a permanent part of the cell's genetic makeup. This integration enables the ...